Biomedical and Translational Informatics Laboratory

  • Burke, M. F., Morley, M. P., Yang, Y., Drivas, T. G., Choe, D., Day, S., Musunuru, K., Li, M., Ritchie, M., & Cappola, T. P. (2021). Abstract 9872: Cardiac Enhancer Variants at the Mtss1 Locus Are Associated with Smaller, More Contractile Hearts. Circulation Genetics and Genomics, 144(A9872). https://doi.org/https://www.ahajournals.org/doi/abs/10.1161/circ.144.suppl_1.9872
  • D’Antonio, M., Nguyen, J. P., Arthur, T. D., Matsui, H., D’Antonio-Chronowska, A., Frazer, K. A., Neale, B. M., Daly, M., Ganna, A., Stevens, C., Pathak, G. A., Andrews, S. J., Kanai, M., Cordioli, M., Ganna, A., Karjalainen, J., Pathak, G. A., Polimanti, R., Andrews, S. J., … Zyndorf, M. (2021). SARS-COV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues. Cell Reports, 37(7), 110020. https://doi.org/10.1016/j.celrep.2021.110020
  • Bone, W.P., Siewert, K.M., Jha, A. et al. Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traits. Alz Res Therapy 13, 34 (2021). https://doi.org/10.1186/s13195-021-00773-z
  • Rosenthal, E.A., Crosslin, D.R., Gordon, A.S. et al. Association between triglycerides, known risk SNVs and conserved rare variation in SLC25A40 in a multi-ancestry cohort. BMC Med Genomics 14, 11 (2021). https://doi.org/10.1186/s12920-020-00854-2
  • Sun, L., Surya, S., Goodman, N. G., Le, A. N., Kelly, G., Owoyemi, O., Desai, H., Zheng, C., DeLuca, S., Good, M. L., Hussain, J., Jeffries, S. D., Kry, Y. R., Kugler, E. M., Mansour, M., Ndicu, J., Osei-Akoto, A., Prior, T., Pundock, S. L., … DeMichele, A. (2021). SARS-COV-2 seropositivity and seroconversion in patients undergoing active cancer-directed therapy. JCO Oncology Practice, 17(12). https://doi.org/10.1200/op.21.00113
  • Drivas, T.G., Lucas, A. & Ritchie, M.D. eQTpLot: a user-friendly R package for the visualization of colocalization between eQTL and GWAS signals. BioData Mining 14, 32 (2021). https://doi.org/10.1186/s13040-021-00267-6
  • Abramoff, B. A., Dillingham, T. R., Caldera, F. E., Ritchie, M. D., & Pezzin, L. E. (2021). Inpatient rehabilitation outcomes after severe COVID-19 infections. American Journal of Physical Medicine & Rehabilitation, 100(12), 1109–1114. https://doi.org/10.1097/phm.0000000000001885
  • COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19. Nature 600, 472–477 (2021). https://doi.org/10.1038/s41586-021-03767-x
  • Graham, S.E., Clarke, S.L., Wu, KH.H. et al. The power of genetic diversity in genome-wide association studies of lipids. Nature 600, 675–679 (2021). https://doi.org/10.1038/s41586-021-04064-3
  • Zhang X, Li R, Ritchie MD. Statistical Impact of Sample Size and Imbalance on Multivariate Analysis in silico and A Case Study in the UK Biobank. AMIA Annu Symp Proc. 2021 Jan 25;2020:1383-1391. PMID: 33936514; PMCID: PMC8075427.
  • Drivas, T. G., Lucas, A., & Ritchie, M. D. (2021). EQTpLot: A user-friendly R package for the visualization of colocalization between eqtl and GWAS signals. BioData Mining, 14(1). https://doi.org/10.1186/s13040-021-00267-6