Biomedical and Translational Informatics Laboratory

Synthesis-View Downloads

What is Synthesis-View ?

Synthesis-View is software for data visualization. With Synthesis-View, through the use of stacked data-tracks, information on SNP genomic locations, presence of the SNP in a specific study or analysis, as well as related information such as genetic effect size and summary phenotype information, can be plotted according to user preference. Through these data visualizations, rapid comparisons of multiple forms of information are possible, not easily achievable through reviewing results in tabular form alone.

Why use Synthesis-View ?

Visualization of the complex data arising from current genetic studies is an integral part of interpreting as well as sharing these complex and multi-layered results. For example, significant GWAS findings are being further investigated for replication and characterization, both in the populations in which the initial GWAS findings were discovered (such as European-Americans) as well as in new cohorts and populations. To increase power, meta-analysis is often used to combine results from multiple research sites. Multiple independent and correlated phenotypic measurements may be included in these analyses, such as measurements of cardiovascular disease and related biomarkers (lipids, inflammation, etc). Many of these studies characterize less than 100 SNPs. The software "Synthesis-View" has been developed to visually synthesize multiple pieces of information of interest from these studies with the flexibility to perform multiple types of data comparisons.

Link to Web-based Synthesis-View

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